CHASM software is intended for those with substantial bioinformatics and Linux system expertise and access to a large-memory Linux server. Other interested users can run CHASM on the CRAVAT web server. CHASM is free for non-commercial use. For more details please refer to our Software License. Commercial users should contact the Johns Hopkins Technology Transfer office .
Carter H, Chen S, Isik L, Tyekucheva S, Velculescu VE, Kinzler KW, Vogelstein B, Karchin R.(2009) Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations.Cancer Research. 69(16):6660-7
Carter H, Samayoa J, Hruban RH, Karchin R (2010) Prioritization of driver mutations in pancreatic cancer using cancer-specific high-throughput annnotation of somatic mutations (CHASM). Cancer Biology & Therapy. Sep 31;10(6):582-7.
Hannah Carter hcarte10 at gmail dot com
For issues with CHASM run on the web with CRAVAT, please contact Rick Kim rkim at insilico dot us dot com
This is a beta version of the CHASM documentation page. Please contact the primary developer with feedback, suggestions, and requests to improve this page.