Most requested datasets from our publications

If the dataset you are interested in is not listed here, contact Rachel Karchin karchin at jhu dot edu

Functional Impact of missense variants in BRCA1 predicted by supervised learning

PLoS Comput Biol. 2007 Feb 16;3(2):e26

Extreme phenotype yeast mutants in TP53 from Kato et al. (PNAS 2003)

BRCA1 BRCT domain variants with transactivation assay labels

BRCA1 BRCT domain variants of undetermined significance in Breast Information Core (BIC) database

Cancer-Specific High-Throughput Annotation of Somatic Mutations (CHASM):
Computational Prediction of Driver Missense Mutations

Cancer Res 2009 69: 6660-6667

CHASM training set (freeze from August 2009) (ZIPPED archive)

 

LS-SNP/PDB: annotated non-synonymous SNPs mapped to Protein Data Bank structures

Bioinformatics 2009 25(11): 1431-1432

Downloadable extracts from LS-SNP/PDB