BOMP @ Karchin lab

BOMP (Burden or Mutation Position gene scoring tool)

software uses a novel hybrid likelihood model to identify phenotype-associated genes from sequencing data in case/control study designs.

BOMP runs on Java >= 1.6.0 Current release is BOMP 1.0. last updated on 01/23/2013. BOMP is free for non-commercial use. Commercial users should contact the Johns Hopkins Technology Transfer office.

Documentation for the user

Download BOMP jar file here. The jar file should be installed in your Java path.


(L) Burden and Position Distribution statistics
(R) How is BOMP different from VT and SKAT?

Documentation for the developer

Download BOMP source code here
For documentation details, please contact the primary developer.

Example workflow

Short tutorial on how to run BOMP

Primary citations

If you use BOMP in a publication, please cite:

Chen YC, Carter H, Parla J, Kramer M, Goes FS, Pirooznia M, Zandi PP, McCombie WR, Potash JB, Karchin R (2013) A hybrid likelihood model for sequence-based disease association studies PLoS Genetics. 9(1): e1003224

Software primary contact/developer

Yun-ching Chen  yunching dot chen at gmail dot com

This is a beta version of the BOMP documentation page. Please contact the primary developer with feedback, suggestions, and requests to improve this page.