Scores from the most recent version CHASM3.1 can be retrieved automatically with the CRAVAT5.0 server
CHASM software is intended for those with substantial bioinformatics and Linux system expertise and access to a large-memory Linux server. CHASM is free for non-commercial use. For more details please refer to our Software License. Commercial users should contact the Johns Hopkins Technology Transfer office .
Carter H, Chen S, Isik L, Tyekucheva S, Velculescu VE, Kinzler KW, Vogelstein B, Karchin R.(2009) Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations.Cancer Research. 69(16):6660-7
Carter H, Samayoa J, Hruban RH, Karchin R (2010) Prioritization of driver mutations in pancreatic cancer using cancer-specific high-throughput annnotation of somatic mutations (CHASM). Cancer Biology & Therapy. Sep 31;10(6):582-7.
Hannah Carter hcarte10 at gmail dot com
For issues with CHASM run on the web with CRAVAT, please contact Rick Kim rkim at insilico dot us dot com