LABEL CLASS ASA-MUT RSA-MUT ASA-WT RSA-WT Delt-Res-Chrg Delt-Res-Vol Delt-Res-Pol Pos-cons-score Rel-Entropy Grantham Buried-charge MUT-NUMVI MUT-NUMVP PHI PSI 6A-methyl-count A119T N 86 0.606 49 0.462 0 -0.917 0.4 -6.8625 0.26 58 0 1 4 -68.9 155.7 11 A129D N 123 0.755 71 0.67 1 -0.75 10.8 -11.405 0.0937 126 0 0 1 -62.1 -40.2 10 A129G N 67 0.798 71 0.67 0 0.95 0.6 -11.3 0.0937 60 0 0 1 -62.1 -40.2 7 A129P N 95 0.699 71 0.67 0 -0.803 1.8 -11.329 0.0937 27 0 0 7 -62.1 -40.2 7 A129S N 94 0.723 71 0.67 0 -0.0133 1 -12.676 0.0937 99 0 0 2 -62.1 -40.2 9 A129T N 107 0.754 71 0.67 0 -0.917 0.4 -11.547 0.0937 58 0 0 2 -62.1 -40.2 11 A129V N 107 0.754 71 0.67 0 -1.71 -1 -12.056 0.0937 64 0 0 1 -62.1 -40.2 10 A138G D 21 0.25 29 0.274 0 0.95 0.6 -7.2291 0.307 60 0 0 0 56.8 6.7 15 A138P D 33 0.243 29 0.274 0 -0.803 1.8 -7.6453 0.307 27 0 1 16 56.8 6.7 15 A138S N 39 0.3 29 0.274 0 -0.0133 1 -7.133 0.307 99 0 0 4 56.8 6.7 16 A159D D 1 0.00613 1 0.00943 1 -0.75 10.8 -7.7044 0.461 126 1 0 8 -125.5 132.5 22 A159G D 0 0 1 0.00943 0 0.95 0.6 -7.0621 0.461 60 0 0 0 -125.5 132.5 19 A159P D 0 0 1 0.00943 0 -0.803 1.8 -7.4928 0.461 27 0 4 21 -125.5 132.5 18 A159S N 0 0 1 0.00943 0 -0.0133 1 -6.5488 0.461 99 0 0 0 -125.5 132.5 20 A159T N 1 0.00704 1 0.00943 0 -0.917 0.4 -6.8092 0.461 58 0 0 5 -125.5 132.5 21 A159V D 0 0 1 0.00943 0 -1.71 -1 -6.1694 0.461 64 0 0 17 -125.5 132.5 20 A161D D 11 0.0675 10 0.0943 1 -0.75 10.8 -8.812 0.25 126 1 0 9 -104.4 138.6 26 A189V N 9 0.0634 4 0.0377 0 -1.71 -1 -9.0669 0.251 64 0 0 11 -87.3 125.5 13 A276D D 79 0.485 70 0.66 1 -0.75 10.8 -7.3491 0.433 126 0 0 0 -72.8 -45.2 7 A276P D 83 0.61 70 0.66 0 -0.803 1.8 -7.262 0.433 27 0 0 1 -72.8 -45.2 6 C124F N 6 0.0305 14 0.104 0 -2.71 -1.7 -12.01 0.449 205 0 0 8 -156.8 122.2 19 C124G D 18 0.214 14 0.104 0 1.61 1 -11.084 0.449 159 0 0 1 -156.8 122.2 11 C124R D 6 0.0242 14 0.104 -1 -2.16 14.3 -10.985 0.449 180 1 0 12 -156.8 122.2 21 C124S N 15 0.115 14 0.104 0 0.65 1.4 -11.524 0.449 112 0 0 1 -156.8 122.2 13 C124Y N 8 0.036 14 0.104 0 -2.84 2.7 -11.174 0.449 194 0 0 9 -156.8 122.2 20 C135F D 0 0 0 0 0 -2.71 -1.7 -8.5422 0.856 205 0 0 25 -154.3 170.0 19 C135G D 3 0.0357 0 0 0 1.61 1 -9.2165 0.856 159 0 0 0 -154.3 170.0 15 C135R D 0 0 0 0 -1 -2.16 14.3 -9.1342 0.856 180 1 0 38 -154.3 170.0 22 C135S D 0 0 0 0 0 0.65 1.4 -8.8552 0.856 112 0 0 0 -154.3 170.0 18 C135Y D 0 0 0 0 0 -2.84 2.7 -8.9716 0.856 194 0 1 32 -154.3 170.0 24 C141G D 1 0.0119 0 0 0 1.61 1 -8.356 0.383 159 0 0 1 -128.0 96.6 9 C141R D 0 0 0 0 -1 -2.16 14.3 -8.4856 0.383 180 1 2 29 -128.0 96.6 18 C141W D 0 0 0 0 0 -3.98 0.1 -9.4066 0.383 215 0 1 68 -128.0 96.6 17 C141Y D 4 0.018 0 0 0 -2.84 2.7 -8.474 0.383 194 0 4 50 -128.0 96.6 17 C176R D 19 0.0766 2 0.0148 -1 -2.16 14.3 -6.2471 4.05 180 1 0 8 -66.3 154.3 21 C176S D 2 0.0154 2 0.0148 0 0.65 1.4 -5.0968 4.05 112 0 0 0 -66.3 154.3 14 C176W D 28 0.123 2 0.0148 0 -3.98 0.1 -7.1909 4.05 215 0 1 11 -66.3 154.3 19 C182F N 49 0.249 37 0.274 0 -2.71 -1.7 -12.8 0.0591 205 0 0 11 -154.7 130.3 11 C182R N 47 0.19 37 0.274 -1 -2.16 14.3 -14.021 0.0591 180 0 0 8 -154.7 130.3 15 C182S N 30 0.231 37 0.274 0 0.65 1.4 -9.7615 0.0591 112 0 0 3 -154.7 130.3 8 C182W N 61 0.269 37 0.274 0 -3.98 0.1 -12.893 0.0591 215 0 0 8 -154.7 130.3 9 C229F N 56 0.284 10 0.0741 0 -2.71 -1.7 -11.591 0.262 205 0 0 4 -160.7 146.1 11 C229S N 7 0.0538 10 0.0741 0 0.65 1.4 -12.163 0.262 112 0 0 1 -160.7 146.1 10 C229Y N 15 0.0676 10 0.0741 0 -2.84 2.7 -12.489 0.262 194 0 11 64 -160.7 146.1 11 C238F D 0 0 0 0 0 -2.71 -1.7 -5.7738 3.96 205 0 1 30 -154.5 162.4 24 C238G D 2 0.0238 0 0 0 1.61 1 -5.3138 3.96 159 0 0 2 -154.5 162.4 20 C238S D 0 0 0 0 0 0.65 1.4 -5.0379 3.96 112 0 0 4 -154.5 162.4 24 C238W D 15 0.0661 0 0 0 -3.98 0.1 -7.1012 3.96 215 0 4 83 -154.5 162.4 29 C238Y D 0 0 0 0 0 -2.84 2.7 -5.9929 3.96 194 0 5 34 -154.5 162.4 25 C242F D 53 0.269 15 0.111 0 -2.71 -1.7 -5.7965 3.98 205 0 0 4 -42.7 106.7 14 C242G D 15 0.179 15 0.111 0 1.61 1 -5.3336 3.98 159 0 0 3 -42.7 106.7 12 C242R D 88 0.355 15 0.111 -1 -2.16 14.3 -6.182 3.98 180 0 0 4 -42.7 106.7 16 C242S D 15 0.115 15 0.111 0 0.65 1.4 -5.0529 3.98 112 0 0 3 -42.7 106.7 14 C242W D 80 0.352 15 0.111 0 -3.98 0.1 -7.1239 3.98 215 0 0 6 -42.7 106.7 14 C242Y D 53 0.239 15 0.111 0 -2.84 2.7 -6.0184 3.98 194 0 0 4 -42.7 106.7 14 C275F D 65 0.33 9 0.0667 0 -2.71 -1.7 -5.7683 3.95 205 0 0 5 -152.0 178.1 14 C275G D 9 0.107 9 0.0667 0 1.61 1 -5.3089 3.95 159 0 0 0 -152.0 178.1 12 C275R D 90 0.363 9 0.0667 -1 -2.16 14.3 -6.1539 3.95 180 0 0 8 -152.0 178.1 16 C275W D 92 0.405 9 0.0667 0 -3.98 0.1 -7.0951 3.95 215 0 0 7 -152.0 178.1 15 C275Y D 88 0.396 9 0.0667 0 -2.84 2.7 -5.9866 3.95 194 0 0 6 -152.0 178.1 14 C277F D 67 0.34 34 0.252 0 -2.71 -1.7 -5.8545 2.06 205 0 0 4 -117.8 78.9 14 C277G D 10 0.119 34 0.252 0 1.61 1 -5.2259 2.06 159 0 0 1 -117.8 78.9 12 C277R D 109 0.44 34 0.252 -1 -2.16 14.3 -5.6845 2.06 180 0 0 5 -117.8 78.9 16 C277W D 93 0.41 34 0.252 0 -3.98 0.1 -6.9554 2.06 215 0 0 4 -117.8 78.9 16 C277Y D 30 0.135 34 0.252 0 -2.84 2.7 -5.7642 2.06 194 0 1 38 -117.8 78.9 16 D148A N 78 0.736 125 0.767 -1 0.75 -10.8 -12.095 0.135 126 0 0 1 -89.4 -25.7 6 D148E N 156 0.804 125 0.767 0 -0.91 -1 -14.288 0.135 45 0 0 1 -89.4 -25.7 7 D148N N 123 0.783 125 0.767 -1 -0.1 -4.4 -12.012 0.135 23 0 0 1 -89.4 -25.7 8 D184A N 30 0.283 29 0.178 -1 0.75 -10.8 -9.5303 0.253 126 0 0 2 -62.0 -0.2 7 D184E N 33 0.17 29 0.178 0 -0.91 -1 -10.292 0.253 45 0 0 4 -62.0 -0.2 15 D184G N 29 0.345 29 0.178 -1 1.7 -10.2 -9.5162 0.253 94 0 0 1 -62.0 -0.2 7 D184H N 33 0.179 29 0.178 -2 -1.4 -6.2 -10 0.253 81 0 0 13 -62.0 -0.2 14 D184N N 30 0.191 29 0.178 -1 -0.1 -4.4 -9.5155 0.253 23 0 0 2 -62.0 -0.2 13 D184V N 35 0.246 29 0.178 -1 -0.963 -11.8 -9.8446 0.253 152 0 0 4 -62.0 -0.2 10 D184Y N 39 0.176 29 0.178 -1 -2.75 -8.5 -10.046 0.253 160 0 0 14 -62.0 -0.2 15 D186A N 87 0.821 75 0.46 -1 0.75 -10.8 -8.788 0.393 126 0 0 4 -77.2 26.2 7 D186E N 99 0.51 75 0.46 0 -0.91 -1 -8.9515 0.393 45 0 0 4 -77.2 26.2 16 D186G N 73 0.869 75 0.46 -1 1.7 -10.2 -8.6661 0.393 94 0 0 2 -77.2 26.2 6 D186H N 89 0.484 75 0.46 -2 -1.4 -6.2 -9.2394 0.393 81 0 0 4 -77.2 26.2 13 D186N N 91 0.58 75 0.46 -1 -0.1 -4.4 -8.65 0.393 23 0 1 3 -77.2 26.2 11 D186V N 113 0.796 75 0.46 -1 -0.963 -11.8 -9.761 0.393 152 0 0 3 -77.2 26.2 9 D186Y N 92 0.414 75 0.46 -1 -2.75 -8.5 -9.121 0.393 160 0 0 4 -77.2 26.2 14 D208A D 26 0.245 49 0.301 -1 0.75 -10.8 -6.5957 0.782 126 0 1 7 11.1 104.5 12 D208N N 61 0.389 49 0.301 -1 -0.1 -4.4 -6.3155 0.782 23 0 1 7 11.1 104.5 12 D208V D 39 0.275 49 0.301 -1 -0.963 -11.8 -7.5864 0.782 152 0 1 10 11.1 104.5 16 D208Y D 122 0.55 49 0.301 -1 -2.75 -8.5 -7.7522 0.782 160 0 1 6 11.1 104.5 12 D228E N 154 0.794 122 0.748 0 -0.91 -1 -6.4262 0.714 45 0 0 3 -99.6 6.6 6 D228G N 50 0.595 122 0.748 -1 1.7 -10.2 -8.8369 0.714 94 0 0 1 -99.6 6.6 5 D228V N 99 0.697 122 0.748 -1 -0.963 -11.8 -9.1919 0.714 152 0 0 3 -99.6 6.6 6 D259A D 28 0.264 44 0.27 -1 0.75 -10.8 -10.006 0.278 126 0 0 0 -78.1 178.2 14 D259E D 86 0.443 44 0.27 0 -0.91 -1 -10.167 0.278 45 0 0 1 -78.1 178.2 15 D259H D 69 0.375 44 0.27 -2 -1.4 -6.2 -10.388 0.278 81 0 0 2 -78.1 178.2 14 D259V D 40 0.282 44 0.27 -1 -0.963 -11.8 -10.379 0.278 152 0 0 2 -78.1 178.2 15 D259Y D 109 0.491 44 0.27 -1 -2.75 -8.5 -10.617 0.278 160 0 1 2 -78.1 178.2 14 D281A D 6 0.0566 9 0.0552 -1 0.75 -10.8 -5.04 2.45 126 0 0 0 -65.9 -29.9 17 D281E D 33 0.17 9 0.0552 0 -0.91 -1 -3.9972 2.45 45 0 0 2 -65.9 -29.9 18 D281G D 5 0.0595 9 0.0552 -1 1.7 -10.2 -4.7583 2.45 94 0 0 0 -65.9 -29.9 15 D281H D 33 0.179 9 0.0552 -2 -1.4 -6.2 -5.7749 2.45 81 0 0 0 -65.9 -29.9 17 D281N D 17 0.108 9 0.0552 -1 -0.1 -4.4 -4.1988 2.45 23 0 0 0 -65.9 -29.9 17 D281V D 10 0.0704 9 0.0552 -1 -0.963 -11.8 -6.1078 2.45 152 0 0 3 -65.9 -29.9 19 D281Y D 66 0.297 9 0.0552 -1 -2.75 -8.5 -6.2225 2.45 160 0 0 3 -65.9 -29.9 17 E171A N 28 0.264 38 0.196 -1 1.66 -9.8 -6.1981 0.873 107 0 0 1 -76.0 137.9 9 E171G D 28 0.333 38 0.196 -1 2.61 -9.2 -6.885 0.873 98 0 0 1 -76.0 137.9 9 E171K N 68 0.332 38 0.196 -2 -1.01 0.6 -6.1919 0.873 56 0 0 2 -76.0 137.9 16 E198A N 36 0.34 74 0.381 -1 1.66 -9.8 -6.2519 0.796 107 0 0 0 -106.9 162.9 8 E198K N 111 0.541 74 0.381 -2 -1.01 0.6 -5.7801 0.796 56 0 0 0 -106.9 162.9 12 E198Q N 80 0.404 74 0.381 -1 -0.18 -4.1 -6.1911 0.796 29 0 0 0 -106.9 162.9 10 E198V N 60 0.423 74 0.381 -1 -0.0533 -10.8 -6.8773 0.796 121 0 0 2 -106.9 162.9 10 E204A N 39 0.368 96 0.495 -1 1.66 -9.8 -10.824 0.152 107 0 0 1 -124.2 148.7 10 E204K N 127 0.62 96 0.495 -2 -1.01 0.6 -11.512 0.152 56 0 0 0 -124.2 148.7 13 E204Q N 107 0.54 96 0.495 -1 -0.18 -4.1 -11.482 0.152 29 0 0 1 -124.2 148.7 12 E224A N 63 0.594 130 0.67 -1 1.66 -9.8 -8.74 0.476 107 0 0 0 -81.6 146.0 5 E224D N 120 0.736 130 0.67 0 0.91 1 -8.7739 0.476 45 0 0 0 -81.6 146.0 5 E224G N 44 0.524 130 0.67 -1 2.61 -9.2 -9.2071 0.476 98 0 0 0 -81.6 146.0 5 E224Q N 151 0.763 130 0.67 -1 -0.18 -4.1 -9.2984 0.476 29 0 0 0 -81.6 146.0 6 E224V N 100 0.704 130 0.67 -1 -0.0533 -10.8 -8.794 0.476 121 0 0 0 -81.6 146.0 6 E258A D 7 0.066 18 0.0928 -1 1.66 -9.8 -4.9053 1.95 107 0 0 0 -128.9 151.4 15 E258D D 9 0.0552 18 0.0928 0 0.91 1 -4.1276 1.95 45 1 0 1 -128.9 151.4 21 E258G D 6 0.0714 18 0.0928 -1 2.61 -9.2 -5.4065 1.95 98 0 0 0 -128.9 151.4 14 E258K D 49 0.239 18 0.0928 -2 -1.01 0.6 -4.6778 1.95 56 0 0 0 -128.9 151.4 22 E258Q D 17 0.0859 18 0.0928 -1 -0.18 -4.1 -4.8685 1.95 29 0 0 1 -128.9 151.4 21 E258V D 4 0.0282 18 0.0928 -1 -0.0533 -10.8 -5.749 1.95 121 0 0 4 -128.9 151.4 19 E271D N 17 0.104 25 0.129 0 0.91 1 -6.6597 0.58 45 1 0 3 -71.3 150.6 21 E271K D 42 0.205 25 0.129 -2 -1.01 0.6 -6.7067 0.58 56 0 0 9 -71.3 150.6 23 E285A N 22 0.208 43 0.222 -1 1.66 -9.8 -6.6885 1.22 107 0 0 1 -67.4 -30.2 17 E285K D 89 0.434 43 0.222 -2 -1.01 0.6 -6.5898 1.22 56 0 0 1 -67.4 -30.2 19 E285Q N 68 0.343 43 0.222 -1 -0.18 -4.1 -6.6866 1.22 29 0 0 0 -67.4 -30.2 18 E285V D 40 0.282 43 0.222 -1 -0.0533 -10.8 -7.753 1.22 121 0 0 2 -67.4 -30.2 19 E286A D 36 0.34 49 0.253 -1 1.66 -9.8 -6.0465 0.956 107 0 0 0 -69.3 -35.2 15 E286D D 47 0.288 49 0.253 0 0.91 1 -5.5214 0.956 45 0 0 0 -69.3 -35.2 20 E286G D 28 0.333 49 0.253 -1 2.61 -9.2 -6.6108 0.956 98 0 0 0 -69.3 -35.2 14 E286K D 93 0.454 49 0.253 -2 -1.01 0.6 -5.7588 0.956 56 0 0 1 -69.3 -35.2 21 E286Q D 57 0.288 49 0.253 -1 -0.18 -4.1 -5.6934 0.956 29 0 3 3 -69.3 -35.2 20 E286V D 45 0.317 49 0.253 -1 -0.0533 -10.8 -6.8062 0.956 121 0 0 0 -69.3 -35.2 20 E287A N 79 0.745 131 0.675 -1 1.66 -9.8 -8.924 0.355 107 0 0 1 -67.9 -43.7 7 E287D N 129 0.791 131 0.675 0 0.91 1 -9.0074 0.355 45 0 0 1 -67.9 -43.7 8 E287G N 64 0.762 131 0.675 -1 2.61 -9.2 -8.9881 0.355 98 0 0 1 -67.9 -43.7 6 E287Q N 156 0.788 131 0.675 -1 -0.18 -4.1 -8.9695 0.355 29 0 0 1 -67.9 -43.7 9 E287V N 113 0.796 131 0.675 -1 -0.0533 -10.8 -9.5028 0.355 121 0 0 2 -67.9 -43.7 9 F109C D 9 0.0667 0 0 0 2.71 1.7 -7.1438 1.68 205 0 0 4 -69.4 121.9 17 F109I D 1 0.00592 0 0 0 0.773 0.6 -5.2487 1.68 21 0 0 3 -69.4 121.9 23 F109S D 10 0.0769 0 0 0 3.36 3.1 -6.5801 1.68 155 0 0 1 -69.4 121.9 16 F109V D 6 0.0423 0 0 0 1.66 1.1 -5.3654 1.68 50 0 0 3 -69.4 121.9 20 F113C D 30 0.222 30 0.152 0 2.71 1.7 -7.2529 1.62 205 0 0 0 -129.7 169.3 14 F113I D 33 0.195 30 0.152 0 0.773 0.6 -5.3281 1.62 21 0 0 3 -129.7 169.3 16 F113S D 31 0.238 30 0.152 0 3.36 3.1 -6.6925 1.62 155 0 0 0 -129.7 169.3 13 F113V D 34 0.239 30 0.152 0 1.66 1.1 -5.4494 1.62 50 0 0 1 -129.7 169.3 14 F134C D 4 0.0296 0 0 0 2.71 1.7 -8.0195 2 205 0 0 1 -118.2 126.0 21 F134I D 2 0.0118 0 0 0 0.773 0.6 -6.8556 2 21 0 0 3 -118.2 126.0 26 F134L D 0 0 0 0 0 0.773 0.9 -6.1884 2 22 0 0 3 -118.2 126.0 26 F134S D 5 0.0385 0 0 0 3.36 3.1 -7.5379 2 155 0 0 1 -118.2 126.0 19 F134V D 3 0.0211 0 0 0 1.66 1.1 -6.8725 2 50 0 0 4 -118.2 126.0 23 F212I D 82 0.485 131 0.665 0 0.773 0.6 -10.786 0.0866 21 0 1 11 84.6 10.0 11 F212V D 69 0.486 131 0.665 0 1.66 1.1 -10.778 0.0866 50 0 1 6 84.6 10.0 12 F212Y N 155 0.698 131 0.665 0 -0.123 4.4 -10.886 0.0866 22 0 0 7 84.6 10.0 10 F270C D 10 0.0741 0 0 0 2.71 1.7 -8.831 1.11 205 0 0 2 -149.4 141.4 14 F270I D 2 0.0118 0 0 0 0.773 0.6 -7.0115 1.11 21 0 0 2 -149.4 141.4 19 F270L D 0 0 0 0 0 0.773 0.9 -6.9168 1.11 22 0 0 2 -149.4 141.4 24 F270S D 9 0.0692 0 0 0 3.36 3.1 -8.3165 1.11 155 0 0 0 -149.4 141.4 14 F270V D 2 0.0141 0 0 0 1.66 1.1 -7.1159 1.11 50 0 0 1 -149.4 141.4 17 G105C D 52 0.385 32 0.381 0 -1.61 -1 -6.3561 2.17 159 0 1 12 66.3 -168.3 11 G105S D 45 0.346 32 0.381 0 -0.963 0.4 -4.3827 2.17 56 0 1 13 66.3 -168.3 10 G105V D 67 0.472 32 0.381 0 -2.66 -1.6 -5.7392 2.17 109 0 3 15 66.3 -168.3 10 G108D D 37 0.227 14 0.167 1 -1.7 10.2 -8.618 0.119 94 0 0 9 59.1 52.5 14 G154V D 98 0.69 46 0.548 0 -2.66 -1.6 -6.4854 1 109 0 1 8 118.0 -11.2 9 G187C N 124 0.919 72 0.857 0 -1.61 -1 -11.357 0.363 159 0 0 4 70.6 -45.4 7 G187D N 153 0.939 72 0.857 1 -1.7 10.2 -9.8983 0.363 94 0 0 6 70.6 -45.4 7 G187R N 238 0.96 72 0.857 -1 -3.78 13.3 -9.6638 0.363 125 0 0 5 70.6 -45.4 9 G187S N 111 0.854 72 0.857 0 -0.963 0.4 -10.35 0.363 56 0 0 4 70.6 -45.4 7 G187V N 137 0.965 72 0.857 0 -2.66 -1.6 -10.565 0.363 109 0 1 5 70.6 -45.4 8 G199A N 87 0.821 74 0.881 0 -0.95 -0.6 -7.7146 0.383 60 0 0 4 82.8 -15.7 9 G199V D 113 0.796 74 0.881 0 -2.66 -1.6 -8.7141 0.383 109 0 1 4 82.8 -15.7 10 G226A N 119 1.12 94 1.12 0 -0.95 -0.6 -3.9743 2.01 60 0 0 4 87.8 5.5 5 G244A D 2 0.0189 3 0.0357 0 -0.95 -0.6 -5.3805 0.823 60 0 0 8 101.9 -20.1 13 G244C D 3 0.0222 3 0.0357 0 -1.61 -1 -7.4313 0.823 159 0 1 16 101.9 -20.1 14 G244R D 29 0.117 3 0.0357 -1 -3.78 13.3 -5.2513 0.823 125 1 4 22 101.9 -20.1 21 G244S D 5 0.0385 3 0.0357 0 -0.963 0.4 -5.3402 0.823 56 0 0 14 101.9 -20.1 13 G244V D 5 0.0352 3 0.0357 0 -2.66 -1.6 -6.4642 0.823 109 0 2 30 101.9 -20.1 15 G245A D 1 0.00943 1 0.0119 0 -0.95 -0.6 -4.0916 1.93 60 0 1 6 -116.5 -123.4 15 G245C D 1 0.00741 1 0.0119 0 -1.61 -1 -6.3235 1.93 159 0 1 6 -116.5 -123.4 18 G245D D 1 0.00613 1 0.0119 1 -1.7 10.2 -4.6776 1.93 94 1 0 16 -116.5 -123.4 22 G245R D 0 0 1 0.0119 -1 -3.78 13.3 -5.2468 1.93 125 1 2 58 -116.5 -123.4 25 G245S D 0 0 1 0.0119 0 -0.963 0.4 -4.3909 1.93 56 0 0 8 -116.5 -123.4 17 G245V D 1 0.00704 1 0.0119 0 -2.66 -1.6 -5.6424 1.93 109 0 4 26 -116.5 -123.4 20 G262A D 57 0.538 37 0.44 0 -0.95 -0.6 -4.7502 1.62 60 0 0 6 84.5 -8.7 8 G262C D 83 0.615 37 0.44 0 -1.61 -1 -6.9419 1.62 159 0 0 7 84.5 -8.7 9 G262S D 71 0.546 37 0.44 0 -0.963 0.4 -4.7204 1.62 56 0 0 6 84.5 -8.7 9 G262V D 86 0.606 37 0.44 0 -2.66 -1.6 -6.2338 1.62 109 0 1 11 84.5 -8.7 11 G266E D 0 0 0 0 1 -2.61 9.2 -5.2531 1.9 98 1 1 29 -174.8 151.3 23 G266R D 0 0 0 0 -1 -3.78 13.3 -5.4595 1.9 125 1 1 56 -174.8 151.3 26 G266V D 0 0 0 0 0 -2.66 -1.6 -5.6598 1.9 109 0 2 28 -174.8 151.3 21 G279E D 0 0 0 0 1 -2.61 9.2 -5.9039 0.657 98 1 0 30 -56.6 -51.4 23 H115D N 153 0.939 190 1.03 2 1.4 6.2 -11.192 0.372 81 0 1 3 -73.7 145.9 7 H115L N 170 1.04 190 1.03 1 -0.45 -5.8 -14.239 0.372 99 0 1 4 -73.7 145.9 9 H115N N 162 1.03 190 1.03 1 1.3 1.8 -12.378 0.372 68 0 1 3 -73.7 145.9 7 H115P N 118 0.868 190 1.03 1 1.35 -2.8 -13.975 0.372 77 0 1 4 -73.7 145.9 6 H115Q N 189 0.955 190 1.03 1 0.313 1.1 -9.2256 0.372 24 0 1 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V147G D 39 0.464 29 0.204 0 2.66 1.6 -8.1121 0.513 109 0 0 0 -141.4 152.0 9 V157A D 1 0.00943 1 0.00704 0 1.71 1 -7.3974 1.32 64 0 0 2 -125.0 114.5 23 V157D D 0 0 1 0.00704 1 0.963 11.8 -9.3276 1.32 152 1 0 4 -125.0 114.5 28 V157F D 1 0.00508 1 0.00704 0 -1.66 -1.1 -7.5195 1.32 50 0 0 19 -125.0 114.5 29 V157G D 4 0.0476 1 0.00704 0 2.66 1.6 -8.8989 1.32 109 0 0 0 -125.0 114.5 21 V157L D 1 0.0061 1 0.00704 0 -0.89 -0.2 -8.0814 1.32 32 0 0 6 -125.0 114.5 28 V172D D 20 0.123 20 0.141 1 0.963 11.8 -8.2159 0.314 152 1 0 0 -76.5 131.7 13 V172F D 18 0.0914 20 0.141 0 -1.66 -1.1 -7.9201 0.314 50 0 0 20 -76.5 131.7 14 V172G D 23 0.274 20 0.141 0 2.66 1.6 -8.0518 0.314 109 0 0 0 -76.5 131.7 10 V172I N 25 0.148 20 0.141 0 -0.89 -0.5 -7.3829 0.314 29 0 0 5 -76.5 131.7 15 V173A D 7 0.066 7 0.0493 0 1.71 1 -5.544 1.25 64 0 0 0 -81.5 122.9 15 V173E D 9 0.0464 7 0.0493 1 0.0533 10.8 -6.968 1.25 121 1 0 9 -81.5 122.9 22 V173G D 7 0.0833 7 0.0493 0 2.66 1.6 -7.1281 1.25 109 0 0 0 -81.5 122.9 14 V173L D 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0.0722 2 0.0141 1 0.0533 10.8 -7.3327 1.54 121 1 0 0 -134.9 163.8 21 V218M D 11 0.0585 2 0.0141 0 -0.763 -0.8 -6.3636 1.54 21 0 0 5 -134.9 163.8 23 V225F N 206 1.05 137 0.965 0 -1.66 -1.1 -8.7693 0.234 50 0 0 0 -60.2 134.2 5 V225I N 155 0.917 137 0.965 0 -0.89 -0.5 -8.448 0.234 29 0 0 2 -60.2 134.2 7 V225L N 170 1.04 137 0.965 0 -0.89 -0.2 -8.8322 0.234 32 0 0 2 -60.2 134.2 7 V272E D 1 0.00515 1 0.00704 1 0.0533 10.8 -7.3612 0.374 121 1 0 4 -134.2 145.5 24 V272G D 3 0.0357 1 0.00704 0 2.66 1.6 -7.1464 0.374 109 0 0 0 -134.2 145.5 19 V272L D 1 0.0061 1 0.00704 0 -0.89 -0.2 -6.7907 0.374 32 0 0 3 -134.2 145.5 27 V272M D 1 0.00532 1 0.00704 0 -0.763 -0.8 -7.748 0.374 21 0 0 6 -134.2 145.5 27 V274A D 4 0.0377 2 0.0141 0 1.71 1 -6.6754 1.73 64 0 0 1 -98.8 123.3 12 V274D D 4 0.0245 2 0.0141 1 0.963 11.8 -8.8606 1.73 152 1 0 4 -98.8 123.3 15 V274F D 2 0.0102 2 0.0141 0 -1.66 -1.1 -6.9957 1.73 50 0 0 18 -98.8 123.3 21 V274G D 5 0.0595 2 0.0141 0 2.66 1.6 -8.4082 1.73 109 0 0 1 -98.8 123.3 11 V274I N 2 0.0118 2 0.0141 0 -0.89 -0.5 -6.0859 1.73 29 0 1 9 -98.8 123.3 21 V274L D 2 0.0122 2 0.0141 0 -0.89 -0.2 -5.8551 1.73 32 0 0 10 -98.8 123.3 20 W146G D 12 0.143 76 0.335 0 5.59 0.9 -12.751 0.15 184 0 0 0 -111.9 135.7 14 W146L N 35 0.213 76 0.335 0 2.04 -0.9 -10.328 0.15 61 0 0 1 -111.9 135.7 19 Y107D D 14 0.0859 51 0.23 1 2.75 8.5 -7.4896 1.1 160 1 0 0 -88.7 -0.9 15 Y107F N 25 0.127 51 0.23 0 0.123 -4.4 -5.9631 1.1 22 0 0 0 -88.7 -0.9 15 Y126C D 15 0.111 41 0.185 0 2.84 -2.7 -6.8144 2.12 194 0 0 1 -114.2 134.2 12 Y126D D 21 0.129 41 0.185 1 2.75 8.5 -6.9485 2.12 160 1 0 1 -114.2 134.2 14 Y126F N 31 0.157 41 0.185 0 0.123 -4.4 -4.1954 2.12 22 0 0 3 -114.2 134.2 14 Y126H D 24 0.13 41 0.185 -1 1.35 2.3 -5.6397 2.12 83 1 0 1 -114.2 134.2 14 Y126N D 18 0.115 41 0.185 0 2.65 4.1 -6.5054 2.12 143 0 0 1 -114.2 134.2 13 Y126S D 20 0.154 41 0.185 0 3.49 -1.3 -6.287 2.12 144 0 0 0 -114.2 134.2 11 Y163C D 5 0.037 1 0.0045 0 2.84 -2.7 -7.4532 1.44 194 0 0 0 -72.9 144.9 22 Y163D D 1 0.00613 1 0.0045 1 2.75 8.5 -7.2254 1.44 160 1 0 3 -72.9 144.9 22 Y163F N 0 0 1 0.0045 0 0.123 -4.4 -5.1798 1.44 22 0 0 2 -72.9 144.9 25 Y163H D 0 0 1 0.0045 -1 1.35 2.3 -6.3829 1.44 83 1 0 0 -72.9 144.9 24 Y163N D 2 0.0127 1 0.0045 0 2.65 4.1 -6.9352 1.44 143 0 0 1 -72.9 144.9 25 Y163S D 6 0.0462 1 0.0045 0 3.49 -1.3 -5.9167 1.44 144 0 0 1 -72.9 144.9 21 Y205C D 60 0.444 44 0.198 0 2.84 -2.7 -7.7529 0.642 194 0 0 1 -115.9 125.1 10 Y205D D 47 0.288 44 0.198 1 2.75 8.5 -8.1927 0.642 160 0 0 0 -115.9 125.1 15 Y205F D 47 0.239 44 0.198 0 0.123 -4.4 -7.1138 0.642 22 0 0 0 -115.9 125.1 19 Y205H D 47 0.255 44 0.198 -1 1.35 2.3 -7.9209 0.642 83 0 0 0 -115.9 125.1 17 Y205N D 47 0.299 44 0.198 0 2.65 4.1 -8.0091 0.642 143 0 0 0 -115.9 125.1 15 Y205S D 49 0.377 44 0.198 0 3.49 -1.3 -7.5932 0.642 144 0 0 0 -115.9 125.1 11 Y220C D 16 0.119 4 0.018 0 2.84 -2.7 -9.7424 0.376 194 0 0 2 -82.7 137.6 14 Y220D D 11 0.0675 4 0.018 1 2.75 8.5 -9.2265 0.376 160 1 0 3 -82.7 137.6 14 Y220H D 7 0.038 4 0.018 -1 1.35 2.3 -8.7806 0.376 83 1 0 1 -82.7 137.6 17 Y220N D 10 0.0637 4 0.018 0 2.65 4.1 -9.0997 0.376 143 0 0 2 -82.7 137.6 14 Y220S D 14 0.108 4 0.018 0 3.49 -1.3 -8.7594 0.376 144 0 0 1 -82.7 137.6 11 Y234C D 3 0.0222 1 0.0045 0 2.84 -2.7 -8.5676 1.43 194 0 0 2 -102.0 155.0 17 Y234D D 5 0.0307 1 0.0045 1 2.75 8.5 -8.6668 1.43 160 1 0 0 -102.0 155.0 22 Y234H D 6 0.0326 1 0.0045 -1 1.35 2.3 -7.8573 1.43 83 1 0 0 -102.0 155.0 23 Y234N D 4 0.0255 1 0.0045 0 2.65 4.1 -8.351 1.43 143 0 0 1 -102.0 155.0 21 Y234S D 5 0.0385 1 0.0045 0 3.49 -1.3 -7.8958 1.43 144 0 0 0 -102.0 155.0 15 Y236C D 6 0.0444 0 0 0 2.84 -2.7 -8.5359 2.13 194 0 1 3 -101.5 108.8 25 Y236D D 6 0.0368 0 0 1 2.75 8.5 -8.8929 2.13 160 1 1 4 -101.5 108.8 27 Y236H D 3 0.0163 0 0 -1 1.35 2.3 -7.5573 2.13 83 1 1 3 -101.5 108.8 30 Y236S D 9 0.0692 0 0 0 3.49 -1.3 -8.103 2.13 144 0 1 3 -101.5 108.8 25