Category: 2011

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways W

Wu J, Jiao Y, Dal Molin M, Maitra A, deWilde RF, Wood LD, Eshleman JR, Goggins MG, Wolfgang CL, Canto ML, Schulick RD, Edil BH, CHoti, MA, Adsay V, Kimstra DS, Offerhaus GJA, Klein AP, Kopelovic L, Carter H, Karchin R, Allen PJ, Schmidt CM, Matio Y, Diaz L, Kinzler KW, Papadopolus N, Hruban RH, …

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Sequence analysis of 515 kinase genes in chronic lymphocytic leukemia S

Zhang X, Reis M, Khoriaty R, Li Y, Ouillette P, Samayoa J, Carter H, Karchin R, Li M, Diaz L, Velculescu VE, Kinzler KW, Vogelstein B and Malek SN (2011) Sequence analysis of 515 kinase genes in Chronic Lymphocytic Leukemia. Leukemia. 25(12):1908-10

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Discriminative prediction of mammalian enhancers from DNA sequence D

Lee D, Karchin R, Beer M. (2011) Discriminative prediction of mammalian enhancers from DNA sequence. Genome Research. 21(12):2167-80

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Integrating diverse genomic data using gene sets I

Tyekucheva S, Marchionni L, Karchin R, Parmigianni G. (2011) Integrating diverse genomic data using gene sets. Genome Biology. 23:R105, Oct. 21, 2011

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Yeast two-hybrid junk sequences contain selected linear motifs Y

Liu Y, Woods N, Kim D, Monteiro ANA, Karchin R (2011) Yeast two-hybrid junk sequences contain selected linear motifs. Nucleic Acids Research. 39(19):e128

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Network models of TEM β-lactamase mutations coevolving under antibiotic selection show modular structure and anticipate evolutionary trajectories N

Beleva-Guthrie V, Allen J, Camps M, and Karchin R (2011) Network models of TEM β-lactamase mutations coevolving under antibiotic selection show modular structure and anticipate evolutionary trajectories. PLoS Computational Biology. 7(9):e1002184

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Roles of DNA polymerase I in leading and lagging-strand replication defined by a high-resolution mutation footprint of ColE1 plasmid replication R

Allen J, Simcha D, Ericson N, Alexander D, Troll C, Marquette J, Van Biber B, Hernandez J, Karchin R, Bielas J, Loeb L, Camps M. (2011) Roles of DNA Polymerase I in leading and lagging-strand replication defined by a high-resolution mutational footprint of ColE1 plasmid replication. Nucleic Acids Res. 39(16):7020-7033

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CHASM and SNVBox: toolkit for detecting biologically important single nucleotide mutations in cancer C

Wong WC, Kim D, Carter H, Diekhans M, Ryan M and Karchin R (2011) CHASM and SNVBox: toolkit for detecting biologically important single nucleotide mutations in cancer. Bioinformatics. 27(15):2147-8

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Correlation of somatic mutation and expression identifies genes important in human glioblastoma progression and survival C

Masica DL and Karchin R (2011) Correlation among somatic mutation expression identifies genes important in human glioblastoma progression and survival. Cancer Research. Jul 1;71(13):4550-61

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Integrated genomic analyses of ovarian carcinoma I

Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma. Nature. 2011 Jun 29;474(7353):609-15. doi: 10.1038/nature10166. Erratum in: Nature. 2012 Oct 11;490(7419):298. PMID: 21720365; PMCID: PMC3163504.

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