Category: Preprints

ImmunoNX: a robust bioinformatics workflow to support personalized neoantigen vaccine trials I

Singhal, K., Schmidt, E., Kiwala, S., Goedegebuure, S. P., Miller, C. A., Xia, H., Cotto, K. C., Li, J., Yao, J., Hendrickson, L., Richters, M. M., Hoang, M. H., Khanfar, M., Risch, I., O’Laughlin, S., Myers, N., Vickery, T., Davies, S. R., Du, F., Mooney, T. B., Coffman, A., Chang, G. S., Hundal, J., Garza, …

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Reconstructing clone-resolved transcriptional programs from bulk tumor sequencing R

Lai, J., Yang, Y., Noller, K., Liu, Y., Balan, A., Nagendra, P., Kagohara, L. T., Fertig, E. J., Wood, L. D., & Karchin, R. Reconstructing clone-resolved transcriptional programs from bulk tumor sequencing. bioRxiv. January 15 2026. doi: 10.64898/2026.01.15.699695

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Do Pseudosequences Matter in Neoantigen Prediction? D

Valeria A, Karchin R. Do Pseudosequences Matter in Neoantigen Prediction? bioRxiv. Dec 9 2025. doi: 10.64898/2025.12.09.693250

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Integrative analysis of genomic and transcriptomic data informs precancer progression in the pancreas I

Noller K, Lai J, Lesperance D, Adkins RS, Elhossiny A, Guerrero PA, Rajapakshe KI, Maitra A, Giglio M, Mahurkar A, White O, Di Magliano MP, Ochs MF, Kagohara LT, Wood LD, Karchin R, Fertig EJ. Integrative analysis of genomic and transcriptomic data informs precancer progression in the pancreas. bioRxiv [Preprint]. 2025 Nov 4:2025.11.03.686234. doi: 10.1101/2025.11.03.686234. …

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Longitudinal structural variant phylogenies define tumor evolution under therapeutic selection pressure in metastatic prostate cancer L

Liu Y, Lai J, Markowski MC, Antonarakis ES, De Marzo AM, Yegnasubramanian S, Wood LD, Sena LA, Karchin R. Longitudinal structural variant phylogenies define tumor evolution under therapeutic selection pressure in metastatic prostate cancer. Jan 24, 2026. doi: 10.1101/2025.02.01.636056

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